Math is a daily component of every chemist’s existence. Trends in our field, particularly the emerging roles of big data and data science, make a fundamental understand- ing of math even more important in our careers. However, for a student of chemistry, math can become a daunting obstacle when trying to connect a mathematical calculation to its chemical meaning. We will discuss common student stumbling blocks seen across standard chemistry curriculum including mathematical-chemical relationships in reaction kinetics, biological buffers, and the molecular absorption of light. We hope to provide a platform for discussion that can support mathematical understanding for chemistry majors and potential mathematics applications for math students.